Preheat your oven to 375°F.

Boil salted water in a large pot and cook the penne pasta for 1 minute less than the package instructions suggest.

Brown the ground beef in an oven-safe skillet over medium heat for about 8 minutes, until it’s cooked and no longer pink.

Stir in the minced garlic, Italian seasoning, and optional red pepper flakes; season with salt and pepper to taste.

Combine the Alfredo sauce and half of the mozzarella cheese into the beef mixture, then mix in the cooked penne pasta.

Spread the mixture evenly in the skillet and top with the remaining mozzarella and grated Parmesan cheese.

Bake uncovered in the preheated oven for 10 minutes, then broil for 2-3 minutes until golden brown.